acccCaliforniagoldrush,late1800's:Agunslingingbountyhunter(Mortimer)travelsdeepintothemountainstofindadeadlyApachewarrior(BrotherWolf)whoiswantedbythelaw.AlongthewayhepassesthroughagoldminingTown.TheminershelpdirectMortimertotheApacheandsendhimonhisway.
MortimerenterstheforestandbeginstotracktheApache.Backintown,theminersun-earthanancientmeteor.Theyusetheirpickaxestocrackitopen.Asectionofthemeteorsplitsapartandsporesexplodeoutofit.Thesporesurroundandinfecttheentirepopulationoftheminingcamp.Theyaretransformedintoravenousmutants.
AfteraviciousbattleagainsttheApachewarrior,Mortimerexitstheforestwithhisprisonerinshackles.Theyhikebacktotheminingtowntofindthemselvessurroundedbyahordeofbloodthirstymutants.NowMortimerthegunslingerandBrotherWolftheWarriormustjointogethertosurvivethemutanthordes.WhatensuesisabloodbathofhorrorfortheDeadandtheDamned.